New setup that enables long-term cell cultures in perfusion mode.
Many R&S labs face the challenge of sustaining long-term, stable cell cultures in perfusion mode without manual intervention or culture loss. Manual systems often lead to inconsistent flow control, filter clogging, and unbalanced medium exchange, resulting in unreliable outcomes.
Additionally, laboratories struggle to ensure continuous monitoring and process safety, as traditional setups lack automated feedback and real-time pressure control needed for reproducible results.
We delivered the system that automates long-term cell cultures in perfusion mode with two control loops. The recirculation loop uses a gentle centrifugal pump and QB Multisensor-controlled crossflow to prevent filter clogging. The perfusion loop balances medium exchange via weight-based feedback.
QB Edge control unit
Providing power and data connection to devices2 PUMPS Precise control of fluid flow
CENTRIFUGAL PUMP
Precise control of gentle fluid flow- AGITATOR
Mixing of fluids, ensuring uniform consistency - 1 MULTISENSOR
Real-time data collection from up to 6 sensors - 1 GASFLOW
Ensures precise gas flow,
optimizes performance - PRESSURE SENSOR
gather precise data from
pressure sensors FOAM SENSOR
Using a sophisticated array of light beams, it enables accurate detection
- Dynamic P&ID
- Graph, reports, audit trail
- Remote Access streamlines workflows, maintains data integrity, and accelerates research.
SENSORS. VESSEL.
The setup consisted of pH, temperature, DO, along with a 3 L vessel and an agitator.
Long-term cell cultures in perfusion mode have always meant constant vigilance in the lab - manual adjustments, risk of filter clogging, and variable results. With QB Systems, our team delivered a solution that finally lets researchers trust their process stability and data integrity, all automated and ready in hours. Seeing labs move from hands-on troubleshooting to focus on real experimentation and innovation is what pushes the industry forward.
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We delivered a system that automated long-term cell cultures in perfusion mode, enabling a complete system setup in just two hours and requiring only three months for the development and integration of advanced monitoring features. Researchers benefited from uninterrupted medium exchange, real-time pressure and flow control, and safer, reproducible culture conditions. Implementation delivered a 45% cost reduction compared to market benchmarks, empowering R&D labs with reliable automation for sustained cellular experiments.
Let’s discuss your specific needs and find the right fit.